Rosalie Chiang - Meilin "Mei" Lee
Sandra Oh - Ming Lee (Mei's mother)
Ava Morse - Miriam Mendelsohn
Maitreyi Ramakrishnan - Priya Mangal
Hyein Park - Abby Park
Orion Lee - Jin Lee
Wai Ching Ho - Grandma Wu
Tristan Allerick Chen - Tyler Nguyen-Baker
Lori Tan Chinn - Auntie Chen
Mia Tagano - Auntie Lily