Owen Wilson - Lightning McQueen
Larry the Cable Guy - Mater
Michael Caine - Finn McMissile
Emily Mortimer - Holley Shiftwell
Eddie Izzard - Sir Miles Axlerod
John Turturro - Francesco Bernoulli
Brent Musburger - Brent Mustangburger
Joe Mantegna - Grem
Thomas Kretschmann - Professor Z
John Ratzenberger - Mack